2000-1994

2000

• Role of Residue Y99 in Tissue Plasminogen Activator. Vindigni A, Winfield M, Ayala YM, Di Cera E Protein Sci 2000 Mar;9(3):619-22

1999

• Incorporation of Noncoded Amino Acids Into the N-Terminal Domain 1-47 of Hirudin Yields a Highly Potent and Selective Thrombin Inhibitor. De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A Protein Sci 1999 Oct;8(10):2213-7​
• Energetic Dissection of Specificity in Serine Proteases. Vindigni A Comb Chem High Throughput Screen 1999 Jun;2(3):139-53

1998

• Synthesis and Characterization of More Potent Analogues of Hirudin Fragment 1-47 Containing Non-Natural Amino Acids. De Filippis V, Quarzago D, Vindigni A, Di Cera E, Fontana A Biochemistry 1998 Sep 29;37(39):13507-15
• Role of P225 and the C136-C201 Disulfide Bond in Tissue Plasminogen Activator. Vindigni A, Di Cera E Protein Sci 1998 Aug;7(8):1728-37​

1997

• Site-Specific Dissection of Substrate Recognition by Thrombin. Vindigni A, Dang QD, Di Cera E Nat Biotechnol 1997 Sep;15(9):891-5
• Prevention of Vascular and Neural Dysfunction in Diabetic Rats by C-Peptide. Ido Y, Vindigni A, Chang K, Stramm L, Chance R, Heath WF, DiMarchi RD, Di Cera E, Williamson JR Science 1997 Jul 25;277(5325):563-6
• Energetics of Thrombin-Thrombomodulin Interaction. Vindigni A, White CE, Komives EA, Di Cera E Biochemistry 1997 Jun 3;36(22):6674-81
• Energetic Dissection of Specificity in Serine Proteases. Di Cera E, Vindigni A, Banerjee D In: Thermodymamics and Structure Based Drug Design (Ladbury J, Connelly PR, eds), Landes Co., London, UK, 1997

1996

• Thrombin as an Allosteric Enzyme: A Route to Novel Anticoagulants. Di Cera E, Dang QD, Guinto ER, Vindigni A, Nayal M, Ayala YM, Farazi TA, Krem MM, Wallace TM, BioIt 1996;4:10-13
• Release of Fibrinopeptides by the Slow and Fast Forms of Thrombin. Vindigni A, Di Cera E Biochemistry 1996 Apr 9;35(14):4417-26
• The Core Domain of Hirudin From the Leech Hirudinaria Manillensis. Chemical Modification of a Tryptophan-Containing Synthetic Peptide Analog. De Antoni F, De Filippis V, Altichieri L, Vindigni A, Polverino de Laureto P, Fontana A Adv Exp Med Biol 1996;398:627-33

1995

• Linkage at Steady State: Allosteric Transitions of Thrombin. Di Cera E, Dang QD, Ayala Y, Vindigni A Methods Enzymol 1995;259:127-44
• Identification of Residues Linked to the Slow–>Fast Transition of Thrombin. Guinto ER, Vindigni A, Ayala YM, Dang QD, Di Cera E Proc Natl Acad Sci U S A 1995 Nov 21;92(24):11185-9
• Thermodynamic Investigation of Hirudin Binding to the Slow and Fast Forms of Thrombin: Evidence for Folding Transitions in the Inhibitor and Protease Coupled to Binding. Ayala YM, Vindigni A, Nayal M, Spolar RS, Record MT Jr, Di Cera E J Mol Biol 1995 Nov 10;253(5):787-98
• The Na+ Binding Site of Thrombin. Di Cera E, Guinto ER, Vindigni A, Dang QD, Ayala YM, Wuyi M, Tulinsky A J Biol Chem 1995 Sep 22;270(38):22089-92
• Core Domain of Hirudin From the Leech Hirudinaria Manillensis: Chemical Synthesis, Purification, and Characterization of a Trp3 Analog of Fragment 1-47. De Filippis V, Vindigni A, Altichieri L, Fontana A Biochemistry 1995 Jul 25;34(29):9552-64
• An Allosteric Switch Controls the Procoagulant and Anticoagulant Activities of Thrombin. Dang OD, Vindigni A, Di Cera E Proc Natl Acad Sci U S A 1995 Jun 20;92(13):5977-81

1994

• Probing the Structure of Hirudin From Hirudinaria Manillensis by Limited Proteolysis. Isolation, Characterization and Thrombin-Inhibitory Properties of N-Terminal Fragments. Vindigni A, De Filippis V, Zanotti G, Visco C, Orsini G, Fontana A Eur J Biochem 1994 Dec 1;226(2):323-33