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- Homologous Recombination Deficiency Real-Time Clinical Assays, Ready or Not? Fuh K, Mullen M, Blachut B, Stover E, Konstantinopoulos P, Liu J, Matulonis U, Khabele D, Mosammaparast N, Vindigni A Gynecol Oncol 2020 Dec;159(3):877-886
- TDP-43 Dysfunction Results in R-Loop Accumulation and DNA Replication Defects. Wood M, Quinet A, Lin YL, Davis AA, Pasero P, Ayala YM, Vindigni A J Cell Sci 2020 Sep 28
- Homologous Recombination Deficiency Real-Time Clinical Assays, Ready or Not?Fuh K, Mullen M, Blachut B, Stover E, Konstantinopoulos P, Liu J, Matulonis U, Khabele D, Mosammaparast N, Vindigni A Gynecol Oncol 2020 Sep 20
- ISG15 Fast-Tracks DNA Replication. Meroni A, Vindigni A J Cell Biol 2020 Aug 3;219(8)
- Inhibition of the Translesion Synthesis Polymerase REV1 Exploits Replication Gaps as a Cancer Vulnerability. Nayak S, Calvo JA, Cong K, Peng M, Berthiaume E, Jackson J, Zaino AM, Vindigni A, Hadden MK, Cantor SB Sci Adv 2020 Jun 10;6(24):eaaz7808
- The Multifunctional Protein PACS-1 Is Required for HDAC2- and HDAC3-Dependent Chromatin Maturation and Genomic Stability. Mani C, Tripathi K, Luan S, Clark DW, Andrews JF, Vindigni A, Thomas G, Palle K Oncogene 2020 Mar;39(12):2583-2596
- PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells. Quinet A, Tirman S, Jackson J, Svikovic S, Lemacon D, Carvajal-Maldonado D, Gonzalez-Acosta D, Vessoni AT, Cybulla E, Wood M, Tavis S, Batista LFZ, Mendez J, Sale JE, Vindigni A Mol Cell 2020 Feb 6;77(3):461-474e9
- Defining and Modulating ‘BRCAness’. Byrum AK, Vindigni A, Mosammaparast N Trends Cell Biol 2019 Sep;29(9):740-751
- XLF and H2AX Function in Series to Promote Replication Fork Stability. Chen BR, Quinet A, Byrum AK, Jackson J, Berti M, Thangavel S, Bredemeyer AL, Hindi I, Mosammaparast N, Tyler JK, Vindigni A, Sleckman BP J Cell Biol 2019 Jul 1;218(7):2113-2123
- Ca(2+)-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks From Aberrant Resection. Li S, Lavagnino Z, Lemacon D, Kong L, Ustione A, Ng X, Zhang Y, Wang Y, Zheng B, Piwnica-Worms H, Vindigni A, Piston DW, You Z Mol Cell 2019 Jun 20;74(6):1123-1137e6
- Mitotic Regulators TPX2 and Aurora A Protect DNA Forks During Replication Stress by Counteracting 53BP1 Function. Byrum AK, Carvajal-Maldonado D, Mudge MC, Valle-Garcia D, Majid MC, Patel R, Sowa ME, Gygi SP, Harper JW, Shi Y, Vindigni A, Mosammaparast N J Cell Biol 2019 Feb 4;218(2):422-432
- Perturbing Cohesin Dynamics Drives MRE11 Nuclease-Dependent Replication Fork Slowing. Carvajal-Maldonado D, Byrum AK, Jackson J, Wessel S, Lemacon D, Guitton-Sert L, Quinet A, Tirman S, Graziano S, Masson JY, Cortez D, Gonzalo S, Mosammaparast N, Vindigni A Nucleic Acids Res 2019 Feb 20;47(3):1294-1310
- Superfast DNA Replication Causes Damage in Cancer Cells. Quinet A, Vindigni A Nature 2018 Jul;559(7713):186-187
- A Cell-Intrinsic Interferon-Like Response Links Replication Stress to Cellular Aging Caused by Progerin. Kreienkamp R, Graziano S, Coll-Bonfill N, Bedia-Diaz G, Cybulla E, Vindigni A, Dorsett D, Kubben N, Batista LFZ, Gonzalo S Cell Rep 2018 Feb 20;22(8):2006-2015
- Replication Fork Reversal: Players and Guardians. Quinet A, Lemacon D, Vindigni A Mol Cell 2017 Dec 7;68(5):830-833
- Nucleases Acting at Stalled Forks: How to Reboot the Replication Program With a Few Shortcuts. Pasero P, Vindigni A Annu Rev Genet 2017 Nov 27;51:477-499
- Break-Induced Replication Promotes Formation of Lethal Joint Molecules Dissolved by Srs2. Elango R, Sheng Z, Jackson J, DeCata J, Ibrahim Y, Pham NT, Liang DH, Sakofsky CJ, Vindigni A, Lobachev KS, Ira G, Malkova A Nat Commun 2017 Nov 27;8(1):1790
- A Ubiquitin-Dependent Signalling Axis Specific for ALKBH-Mediated DNA Dealkylation Repair. Brickner JR, Soll JM, Lombardi PM, Vagbo CB, Mudge MC, Oyeniran C, Rabe R, Jackson J, Sullender ME, Blazosky E, Byrum AK, Zhao Y, Corbett MA, Gecz J, Field M, Vindigni A, Slupphaug G, Wolberger C, Mosammaparast N Nature 2017 Nov 16;551(7680):389-393
- DNA Fiber Analysis: Mind the Gap! Quinet A, Carvajal-Maldonado D, Lemacon D, Vindigni A Methods Enzymol 2017;591:55-82
- MRE11 and EXO1 Nucleases Degrade Reversed Forks and Elicit MUS81-Dependent Fork Rescue in BRCA2-Deficient Cells. Lemacon D, Jackson J, Quinet A, Brickner JR, Li S, Yazinski S, You Z, Ira G, Zou L, Mosammaparast N, Vindigni A Nat Commun 2017 Oct 16;8(1):860
- Human Ribonuclease H1 Resolves R-Loops and Thereby Enables Progression of the DNA Replication Fork. Parajuli S, Teasley DC, Murali B, Jackson J, Vindigni A, Stewart SA J Biol Chem 2017 Sep 15;292(37):15216-15224
- Special Issue: “At the Intersection of DNA Replication and Genome Maintenance: From Mechanisms to Therapy”. Vindigni A Biophys Chem 2017 Jun;225:1-2
- Combining Electron Microscopy With Single Molecule DNA Fiber Approaches to Study DNA Replication Dynamics. Vindigni A, Lopes M Biophys Chem 2017 Jun;225:3-9
- The Architectural Chromatin Factor High Mobility Group A1 Enhances DNA Ligase IV Activity Influencing DNA Repair. Pellarin I, Arnoldo L, Costantini S, Pegoraro S, Ros G, Penzo C, Triolo G, Demarchi F, Sgarra R, Vindigni A, Manfioletti G PLoS One 2016 Oct 10;11(10):e0164258
- Topoisomerase IIbeta Mediates the Resistance of Glioblastoma Stem Cells to Replication Stress-Inducing Drugs. Kenig S, Faoro V, Bourkoula E, Podergajs N, Ius T, Vindigni M, Skrap M, Lah T, Cesselli D, Storici P, Vindigni A Cancer Cell Int 2016 Jul 26;16:58
- Kinase-Dead ATM Protein Is Highly Oncogenic and Can Be Preferentially Targeted by Topo-Isomerase I Inhibitors. Yamamoto K, Wang J, Sprinzen L, Xu J, Haddock CJ, Li C, Lee BJ, Loredan DG, Jiang W, Vindigni A, Wang D, Rabadan R, Zha S Elife 2016 Jun 15;5
- Replication Stress: Getting Back on Track. Berti M, Vindigni A Nat Struct Mol Biol 2016 Feb;23(2):103-9
- Structural and Biochemical Characterization of an RNA/DNA Binding Motif in the N-Terminal Domain of RecQ4 Helicases. Marino F, Mojumdar A, Zucchelli C, Bhardwaj A, Buratti E, Vindigni A, Musco G, Onesti S Sci Rep 2016 Feb 18;6:21501