2015

Fourier Transform Infrared Microspectroscopy Reveals Biochemical Changes Associated With Glioma Stem Cell Differentiation
Kenig S, Bedolla DE, Birarda G, Faoro V, Mitri E, Vindigni A, Storici P, Vaccari L
Biophys Chem 2015 Dec;207:90-6

Human RECQ1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights From DNA Complex Structures
Pike AC, Gomathinayagam S, Swuec P, Berti M, Zhang Y, Schnecke C, Marino F, von Delft F, Renault L, Costa A, Gileadi O, Vindigni A
Proc Natl Acad Sci U S A 2015 Apr 7;112(14):4286-91

Rad51-Mediated Replication Fork Reversal Is a Global Response to Genotoxic Treatments in Human Cells
Zellweger R, Dalcher D, Mutreja K, Berti M, Schmid JA, Herrador R, Vindigni A, Lopes M
J Cell Biol 2015 Mar 2;208(5):563-79

DNA2 Drives Processing and Restart of Reversed Replication Forks in Human Cells
Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, Vujanovic M, Zellweger R, Moore H, Lee EH, Hendrickson EA, Cejka P, Stewart S, Lopes M, Vindigni A
J Cell Biol 2015 Mar 2;208(5):545-62

2014

Identification of RECQ1-Regulated Transcriptome Uncovers a Role of RECQ1 in Regulation of Cancer Cell Migration and Invasion
Li XL, Lu X, Parvathaneni S, Bilke S, Zhang H, Thangavel S, Vindigni A, Hara T, Zhu Y, Meltzer PS, Lal A, Sharma S
Cell Cycle 2014;13(15):2431-45

2013

The Two Faces of DNA Repair: Disease and Therapy
Vindigni A, Gonzalo S
Mo Med 2013 Jul-Aug;110(4):314-9

Bioinformatic Analysis of RecQ4 Helicases Reveals the Presence of a RQC Domain and a Zn Knuckle
Marino F, Vindigni A, Onesti S
Biophys Chem 2013 Jul-Aug;177-178:34-9

Human RECQ1 Promotes Restart of Replication Forks Reversed by DNA Topoisomerase I Inhibition
Berti M, Ray Chaudhuri A, Thangavel S, Gomathinayagam S, Kenig S, Vujanovic M, Odreman F, Glatter T, Graziano S, Mendoza-Maldonado R, Marino F, Lucic B, Biasin V, Gstaiger M, Aebersold R, Sidorova JM, Monnat RJ Jr, Lopes M, Vindigni A
Nat Struct Mol Biol 2013 Mar;20(3):347-54

Discovery of ML216, a Small Molecule Inhibitor of Bloom (BLM) Helicase
Rosenthal AS, Dexheimer TS, Nguyen G, Gileadi O, Vindigni A, Simeonov A, Jadhav A, Hickson I, Maloney DJ
Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-2011 Apr 15 [updated 2013 Feb 28]

2012

In Vitro Enzyme Comparative Kinetics: Unwinding of Surface-Bound DNA Nanostructures by RecQ and RecQ1
Parisse P, Vindigni A, Scoles G, Casalis L
J Phys Chem Lett 2012 Dec 6;3(23):3532-7

The Alpha2 Helix in the DNA Ligase IV BRCT-1 Domain Is Required for Targeted Degradation of Ligase IV During Adenovirus Infection
Gilson T, Greer AE, Vindigni A, Ketner G, Hanakahi LA
Virology 2012 Jul 5;428(2):128-35

Proteomic Analysis of Gastric Cancer and Immunoblot Validation of Potential Biomarkers
Kocevar N, Odreman F, Vindigni A, Grazio SF, Komel R
World J Gastroenterol 2012 Mar 21;18(11):1216-28

2011

The Human RECQ1 Helicase Is Highly Expressed in Glioblastoma and Plays an Important Role in Tumor Cell Proliferation
Mendoza-Maldonado R, Faoro V, Bajpai S, Berti M, Odreman F, Vindigni M, Ius T, Ghasemian A, Bonin S, Skrap M, Stanta G, Vindigni A
Mol Cancer 2011 Jul 13;10:83

A Prominent Beta-Hairpin Structure in the Winged-Helix Domain of RECQ1 Is Required for DNA Unwinding and Oligomer Formation
Lucic B, Zhang Y, King O, Mendoza-Maldonado R, Berti M, Niesen FH, Burgess-Brown NA, Pike AC, Cooper CD, Gileadi O, Vindigni A
Nucleic Acids Res 2011 Mar;39(5):1703-17